Support for Every Step™ | TRYNGOLZA™ (olezarsen) Injection

Support for patients taking TRYNGOLZA

We know how difficult living with familial chylomicronemia syndrome (FCS) can be, but with Ionis Every Step, you are not alone. That is why we provide a suite of services when you are prescribed TRYNGOLZA and a dedicated partner for your treatment journey—your Ionis Every Step Patient Education Manager.

Your Patient Education Manager can:

Explain the process to get TRYNGOLZA

Answer your questions about TRYNGOLZA or FCS

Teach you how to inject TRYNGOLZA in person, over the phone, or virtually

Provide services and resources, like nutrition support, to help manage your treatment

Not real patients; actor portrayals.

Representation of TRYNGOLZA patients

Not real patients; actor portrayals.

Getting started with Ionis Every Step for TRYNGOLZA

Signing up for Ionis Every Step is easy and can be done in one of several ways:

1

Complete the Patient Consent Form online

or

2

Call Ionis Every Step at 1-844-789-8744

or

3

Sign the TRYNGOLZA Patient Enrollment and Prescription Form in your doctor’s office

Find a doctor who
specializes in FCS

TRYNGOLZA must be prescribed by a lipid expert (doctor who specializes in FCS and other lipid disorders). Use the link below to visit the Foundation of the National Lipid Association website, where you can search for a lipid expert in your area who may be able to help you determine if TRYNGOLZA is right for you.

Find a lipid expert

Actor portrayal of a doctor speaking to a patient

Actor portrayal of a doctor speaking to a patient

Not real doctor or patient; actor portrayals.

Let’s connectSign up to receive updates about TRYNGOLZA.

FCS=familial chylomicronemia syndrome.

Important safety information and indication

Important safety information

Do not use TRYNGOLZA if you have had a serious allergic reaction to TRYNGOLZA or any of the ingredients in TRYNGOLZA.

Before using TRYNGOLZA, tell your healthcare provider about all of your medical conditions, including if you: are pregnant or plan to become pregnant, and are breastfeeding or plan to breastfeed. It is not known if TRYNGOLZA can harm your unborn baby, or if it passes into your breast milk and if it can harm your baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of TRYNGOLZA?
TRYNGOLZA can cause side effects including allergic reactions that may be serious. Allergic reactions can include redness of the skin, red itchy bumps (hives), swelling of the face, chills or trouble breathing. Stop taking TRYNGOLZA and call your healthcare provider or get emergency help right away if you have any of these symptoms.

The most common side effects of TRYNGOLZA include injection site reactions (such as redness or pain at the injection site), decreased platelet count (blood cells that help to clot blood), and joint pain or stiffness.

These are not all the possible side effects of TRYNGOLZA. Tell your healthcare provider or treatment team about any side effect you may have.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call 1-800-FDA-1088.

Please see full Prescribing Information and Patient Information for TRYNGOLZA.

Indication

TRYNGOLZA (olezarsen) is a prescription medicine used along with diet to reduce triglycerides (fat in the blood) in the treatment of adults with a condition that keeps the body from breaking down fats called familial chylomicronemia syndrome (FCS). It is not known if TRYNGOLZA is safe and effective in children.

Indication

TRYNGOLZA (olezarsen) is a prescription medicine used along with diet to reduce triglycerides (fat in the blood) in the treatment of adults with a condition that keeps the body from breaking down fats called familial chylomicronemia syndrome (FCS). It is not known if TRYNGOLZA is safe and effective in children.

Important safety information

Do not use TRYNGOLZA if you have had a serious allergic reaction to TRYNGOLZA or any of the ingredients in TRYNGOLZA.

Before using TRYNGOLZA, tell your healthcare provider about all of your medical conditions, including if you: are pregnant or plan to become pregnant, and are breastfeeding or plan to breastfeed. It is not known if TRYNGOLZA can harm your unborn baby, or if it passes into your breast milk and if it can harm your baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of TRYNGOLZA?
TRYNGOLZA can cause side effects including allergic reactions that may be serious. Allergic reactions can include redness of the skin, red itchy bumps (hives), swelling of the face, chills or trouble breathing. Stop taking TRYNGOLZA and call your healthcare provider or get emergency help right away if you have any of these symptoms.

The most common side effects of TRYNGOLZA include injection site reactions (such as redness or pain at the injection site), decreased platelet count (blood cells that help to clot blood), and joint pain or stiffness.

These are not all the possible side effects of TRYNGOLZA. Tell your healthcare provider or treatment team about any side effect you may have.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call 1-800-FDA-1088.

Please see full Prescribing Information and Patient Information for TRYNGOLZA.